描 述:Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.Ac-WEHD-CHO是一种非常有效的caspase-1 (ICE)的可逆抑制剂。它具有该酶的最佳四肽识别基序。其Ki值为56 pM,属于最有效的可逆性肽类蛋白酶抑制剂。caspase-8的Ki值为21.1 nM。