Caspase 3 (Apopain) Substrate 1m, fluorogenic
编号：145638
CAS号：169332-61-0
三字母：Ac-Asp-Glu-Val-Asp-AMC
描 述：A continuous fluorometric assay employing Ac-DEVD-AMC has been developed for the measurement of caspase-3, a cysteine protease also called apopain, Yama or CPP-32. The design of this substrate Ac-DEVD-AMC was based on the substrate motif that has been used successfully with caspase-1, using the poly(ADP-ribose) polymerase cleavage site P₁-P₄ tetrapeptide.采用Ac-DEVD-AMC的连续荧光测定已开发用于测量半胱氨酸蛋白酶caspase-3，也称为apopain, Yama或pcp -32。该底物Ac-DEVD-AMC的设计基于已成功用于caspase-1的底物基序，使用聚(adp核糖)聚合酶裂解位点P₁-P₄四肽。
