基质金属蛋白酶MMP-13, Substrate
编号：157369
CAS号：1872435-02-3
三字母：Dnp-Gly-Pro-Leu-Gly-Met-Arg-Gly-Leu-NH2
描 述：Highly sensitive and selective substrate for collagenase-3 (MMP-13) with a kcat/Km value of 4.22 · 10⁶ M⁻¹s⁻¹ (pH = 7.5, T = 37 °C). The kcat/Km value of human collagenase-3 for this synthetic peptide is 1344-, 11-, and 820-fold better than that of related MMPs stromelysin-1 (MMP-3), gelatinase B (MMP-9), and collagenase-1 (MMP-1), respectively.
对胶原酶-3 (MMP-13)具有高度敏感性和选择性的底物，kcat/Km值为4.22·10⁶M毒血症(pH = 7.5, T = 37°C)。该合成肽的人胶原酶-3的kcat/Km值分别是相关MMPs基质溶素-1 (MMP-3)、明胶酶B (MMP-9)和胶原酶-1 (MMP-1)的1344倍、11倍和820倍。
