这种成骨生长肽(OGP)的 C 端片段(H-8640)表现出与OGP相似的全部生物活性。它作为骨形成促进剂和造血刺激剂引起了相当大的关注。
This C-terminal fragment of the osteogenic growth peptide (OGP), (H-8640), showed the full spectrum of OGP-like bioactivities. It has attracted considerable interest as bone anabolic agent and hematopoietic stimulator.
单字母 H2N-YGFGG-OH
多字母 H2N-Tyr-Gly-Phe-Gly-Gly-OH
氨基酸个数 5
分子式 C24H29N5O7
平均分子量(MW) 499.52
精确分子量(Exact Mass)(MW) 499.21
等电点(PI) -
pH=7.0时的净电荷数 1.97
GRAVY 0.14
亲水残基比例 -
消光系数 1490
溶解建议
参考文献:
I.Bab and M.Chorev, Biopolymers, 66, 33 (2002)
Shen L, Cao S, Wang Y, et al. Self-Adaptive Antibacterial Scaffold with Programmed Delivery of Osteogenic Peptide and Lysozyme for Infected Bone Defect Treatment. ACS Appl Mater Interfaces. 2023;15(1):626-637. doi:10.1021/acsami.2c19026