Amylin (8-37) (mouse, rat)是天然Amylin一种截短肽段的类似物,其选择性抑制肌肉组织中胰岛素相关的葡萄糖摄取和糖原沉积。Amylin (8-37) (mouse, rat)是一种稍弱的胰淀素受体 (amylin receptor, AMY) 拮抗剂。
序列(三字母):H-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-Arg-Ser-Ser-Asn-Asn-Leu-Gly-Pro-Val-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
序列(单字母):ATQRLANFLVRSSNNLGPVLPPTNVGSNTY-NH2
分子式:C140H227N43O43
分子量:3200.61
CAS#:138398-61-5
合成方法:Synthetic
存储条件:-20 °C,避光,干燥
应用:Diabetes
参考文献:
Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development【 DOI: 10.1111/bph.13496】