Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) 是在下丘脑中合成的垂体前体十肽，在控制生殖功能中起关键作用。

体外研究：

Luteinizing hormone-releasing hormone (LHRH) is the key hormone in the control of reproductive functions.LHRH acts as an antimitogenic factor through the activation of the Gi-cAMP intracellular signaling pathway. LHRH might act as an inhibitory factor on both cell proliferation and metastatic behavior in melanoma cells[1]. The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) plays a central role in the control of reproduction by stimulating the release of pituitary luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn promote gonadal functions and regulate sex steroid secretion. The effects of LHRH are mediated by high-affinity G protein-coupled LHRH-receptor (LHRH-R) on pituitary gonadotropes. The responses to LHRH vary under different conditions and critically depend on the regimens of administration and doses delivered to gonadotrope cells[2].

单字母 Pyr-HWSYGWLPG-CONH2

CAS No. : 86073-88-3

中文名称：黄体激素释放激素 (LH-RH),蛙鱼
多字母 Pyr-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-CONH2
氨基酸个数 9
分子式 C60H73N15O13
平均分子量(MW) 1212.31
精确分子量(Exact Mass)(MW) 1211.55
等电点(PI) -
pH=7.0时的净电荷数 1.24
GRAVY -0.59
亲水残基比例 -
消光系数 12490
溶解建议

参考文献：

Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression【 DOI: 10.1677/erc.0.0100161】