949100-39-4
2024/12/16 13:54:47
Delcasertib (KAI-9803) 是有效,选择性的δ蛋白激酶C(δPKC) 抑制剂。Delcasertib (KAI-9803) 可改善急性心肌梗死动物模型的缺血再灌注损伤。
Delcasertib (KAI-9803) is composed of a selective δ-protein kinase C (δPKC) inhibitor peptide derived from the δV1-1 portion of δPKC (termed “cargo peptide”), conjugated reversibly to the cell-penetrating peptide 11-amino acid, arginine-rich sequence of the HIV type 1 transactivator protein (TAT47–57; termed “carrier peptide”) via a disulfide bond。
分子量:2880.28
分子式:C120H199N45O34S2
CAS 号:949100-39-4
序列 1:CYGRKKRRQRRR;序列 1':CSFNSYELGSL (Disulfide bridge:Cys1-Cys1’)
外观与性状:粉末状固体
消光系数: -
来源: 人工化学合成,仅限科学研究使用,不得用于人体。
储存条件:负80℃至负20℃
参考文献:
Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction【DOI: 10.1161/CIRCULATIONAHA.107.759167】