Felypressin acetate  (Synonyms: PLV-2 acetate)

产品描述：

Felypressin vinegar (PLV-2 vinegar) 是一种非儿茶酚胺的血管收缩剂，也是一种加压素 1 ( vasopressin 1 ) 激动剂。Felypressin vinegar 广泛用于牙科手术中。

分子式：C46H65N13O11S2.xC2H4O2
CAS 号：914453-97-7
三字母：Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bridge: Cys1-Cys6)

单字母：CFFQNCPKG-NH2 (Disulfide bridge: Cys1-Cys6)

体外研究：

苯赖加压素是一种合成的垂体后叶激素，具有血管收缩特性，广泛用于牙科手术。苯赖加压素的血管收缩作用似乎是由血管平滑肌细胞的 V1 受体介导的

体内研究：

Felypressin can reduce toxicity during dental procedures. Felypressin increases the diastolic blood pressure of hypertensive patients with controlled blood pressure.
Cardiovascular effects of Felypressin (240 ng/kg; intravenous injection) are studied in Wistar rats. Felypressin induces a pressor effect. Felypressin depends on V1 receptors to induce pressor and bradycardic effects, and that it produces a high relationship between bradycardia and mean arterial pressure variation depending on area postrema and central V1 receptors。