GLP-1(7-37)

同义词： 人胰高血糖素样肽-1

分子量：3355.67
分子式：C151H228N40O47
CAS 号：106612-94-6
三字母：His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly

单字母：HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG

产品描述：

GLP-1(7-37) 是一种肠道胰岛素激素，可以增强葡萄糖诱导的胰岛素分泌。

体内研究：

GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats。
Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM。