166184-23-2
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CRGDFPASSC
编号:130659
CAS号:166184-23-2
三字母:H2N-Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys-OH(Disulfide Bridge:Cys1-Cys10)
描 述:CRGDFPASSC is a cyclic RGD-containing decapeptide which binds to the fibrinogen receptor on the platelet surface. This analog with Phe substituted for Ser at position 5 was found to be 3 times more active (IC₅₀ = 2.5 µM) as a platelet aggregation inhibitor than CRGDSPASSC.