Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH2也叫Romurtide, Muroctasin, MDP-Lys(L 18), Ac-muramyl-Ala-D-Isogln-Lys(stearoyl)-OH。通过对Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH2在体液和细胞免疫应答中的辅助活性研究中发现,它可以增强脾淋巴细胞对植物血凝素(PHA)和脂多糖促有丝分裂反应;它还可以促进鼠中羊红细胞抗体的形成。此外,Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH2还可以增强多克隆B细胞在体内和体外的活化。
序列(三字母):Ac-muramyl-Ala-D-Glu(Lys(stearoyl)-OH)-NH2
别名:Romurtide, Muroctasin, MDP-Lys(L 18), Ac-muramyl-Ala-D-Isogln-Lys(stearoyl)-OH
分子式:C43H78N6O13
分子量:887.13
CAS#:78113-36-7
合成方法:Synthetic
存储条件:-20 °C,避光,干燥
应用:Immunomodulating Agents
Induction of tumor necrosis factor-alpha in solid tumor region by the orally administered synthetic muramyl dipeptide analogue, romurtide【DOI: 10.1016/s1567-5769(00)00017-5】