505070-05-3
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Bid BH3 (80-99) is a biological active peptide. (BID is a pro-apoptotic member of the 'BH3-only' (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic γ-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
编号:223495
中文名称: 肽Bid BH3 Peptide
CAS号：505070-05-3
单字母: H2N-EDIIRNIARHLAQVGDSMDR-OH
三字母: H2N-Glu-Asp-Ile-Ile-Arg-Asn-Ile-Ala-Arg-His-Leu-Ala-Gln-Val-Gly-Asp-Ser-Met-Asp-Arg-OH
氨基酸个数: 20
分子式: C95H161N33O32S1
平均分子量: 2309.56
精确分子量: 2308.17
等电点(PI): 7.56
pH=7.0时的净电荷数: 0.21
平均亲水性: 0.53684210526316
疏水性值: -0.6
外观与性状: 粉末状固体
消光系数: -
来源: 人工化学合成，仅限科学研究使用，不得用于人体。
储存条件:负80℃至负20℃
